Kole, Ayeeshik
Cao, Yingchun
Hui, Jie
Bolad, Islam A.
Alloosh, Mouhamad
Cheng, Ji-Xin
Sturek, Michael
Funding for this research was provided by:
National Heart, Lung, and Blood Institute (R01HL125385)
Indiana Clinical and Translational Sciences Institute (Center of Excellence in Cardiovascular Research Grant)
Indiana University (Fortune-Fry Ultrasound Research Fund)
American Heart Association (16POST27480018)
Graduate School, Purdue University (Hugh W. and Edna M. Donnan Fellowship)
Article History
Received: 27 June 2018
Accepted: 19 November 2018
First Online: 28 November 2018
Compliance with Ethical Standards
:
: The authors declare that they have no conflicts of interest.
: All applicable international, national, and/or institutional guidelines for the care and use of animals were followed. The protocols were approved by the Institutional Animal Care and Use Committee at the Indiana University School of Medicine.
: This article does not contain any studies with human participants performed by any of the authors, as approved by exemption, per the use of discarded human tissue, by the Indiana University Institutional Review Board.
: IVPA-US is an emerging catheter-based hybrid imaging technique capable of quantitative localization of arterial lipid in early- to late-stage atherosclerosis. This unique capability permits future longitudinal studies to monitor progression to vulnerable plaque phenotypes and the associated mechanisms of rupture leading to acute coronary syndrome, a leading cause of morbidity and mortality.