Yamamoto, Yutaka http://orcid.org/0000-0001-6147-6828
Yamashiro, Hiroyasu
Toh, Uhi
Kondo, Naoto
Nakamura, Rikiya
Kashiwaba, Masahiro
Takahashi, Masato
Tsugawa, Koichiro
Ishikawa, Takashi
Nakayama, Takahiro
Ohtani, Shoichiro
Takano, Toshimi
Fujisawa, Tomomi
Toyama, Tatsuya
Kawaguchi, Hidetoshi
Mashino, Kojiro
Tanino, Yuichi
Morita, Satoshi
Toi, Masakazu
Ohno, Shinji
Funding for this research was provided by:
Chugai Pharmaceutical
Article History
Received: 4 May 2020
Accepted: 16 July 2020
First Online: 26 July 2020
Compliance with ethical standards
:
: Yamamoto Y reports grants and personal fees from Daiichi-Sankyo, grants and personal fees from Eisai, grants and personal fees from Eli Lilly, grants and personal fees from Takeda, personal fees from Sysmex, personal fees from GE Health Care Japan, personal fees from AstraZeneca, grants and personal fees from Pfizer, grants and personal fees from Novartis, grants and personal fees from Nihon Kayaku, grants and personal fees from Kyowa-Kirin, grants and personal fees from Taiho, grants and personal fees from Chugai, outside the submitted work; and A board member of the Japanese Breast Cancer Society, A board member of the Japan Breast Cancer Research Group. Yamashiro H reports personal fees from Chugai, personal fees from Daiich Sankyo, personal fees from Pfizer, personal fees from Kyowa Kirin, personal fees from Eisai, personal fees from Eli Lilly, personal fees from Takeda, personal fees from Taiho outside the submitted work; Toh U reports remuneration from Chugai, Kyowa Kirin, Daiichi Sankyo, Taiho, Nihon Kayaku and Eisai, outside the submitted work; Kondo N reports personal fees from Chugai, personal fees from Eli Lilly, personal fees from Pfizer, personal fees from AstraZeneca, outside the submitted work; Nakamura R reports personal fees from Chugai, outside the submitted work; Kashiwaba M reports Speaker's bureaus from Chugai, Novartis, Kyowa Kirin, Pfizer, AstraZeneca, Taiho, Eisai, Daiichi Sankyo and Shionogi, outside the submitted work; Takahashi M reports personal fees from Chugai, grants and personal fees from Nippon Kayaku, outside the submitted work; Tsugawa K reports grants and personal fees from AstraZeneca, grants and personal fees from Chugai, grants and personal fees from Eisai, grants and personal fees from Taiho, grants and personal fees from Takeda, grants and personal fees from Nippon Kayaku, grants from MSD, personal fees from Eli Lilly, personal fees from Daiichi Sankyo, personal fees from Pfizer, during the conduct of the study; Ishikawa T reports grants and other from Eisai, grants and other from Nihon Kayaku, grants and other from Chugai, grants and other from Taiho, grants from Sanofi, grants and other from Eli Lilly, other from Pfizer, outside the submitted work; Nakayama T reports personal fees from Chugai, personal fees from Novartis, personal fees from Eli Lilly, personal fees from AstraZeneca, personal fees from Taiho, personal fees from Eisai, personal fees from Takeda, outside the submitted work; Ohtani S reports other from Chugai, other from Eisai, other from AstraZeneca, other from Pfizer, other from Eli Lilly, outside the submitted work; Takano T reports grants and personal fees from Daiichi Sankyo, grants and personal fees from Kyowa Kirin, grants and personal fees from Eisai, personal fees from Pfizer, personal fees from Eli Lilly, grants from Ono, grants from MSD, grants from Merck Serono, grants from Taiho, grants from Novartis, grants from Chugai, outside the submitted work; Fujisawa T reports personal fees from Chugai, personal fees from Eli Lilly, during the conduct of the study; Toyama T reports grants and personal fees from Chugai, grants and personal fees from Novartis, grants and personal fees from Eisai, grants and personal fees from AstraZeneca, personal fees from Eli Lilly, personal fees from Kyowa Kirin, personal fees from Taiho, personal fees from Daiichi Sankyo, personal fees from Nippon Kayaku, personal fees from Pfizer, personal fees from Takeda, during the conduct of the study; Kawaguchi H reports personal fees from Pfizer, personal fees from Chugai, personal fees from AstraZeneca, personal fees from Eli Lilly, personal fees from Eisai, personal fees from Kyowa Kirin, personal fees from Novartis, personal fees from Taiho, personal fees from Takeda, personal fees from Nippon Chemiphar, personal fees from Daiichi Sankyo, during the conduct of the study; Mashino K reports personal fees from Chugai, outside the submitted work; Tanino Y reports grants from Sysmex Corporation, other from Ono, other from Chugai, other from Novartis, other from Pfizer, other from Daiichi-Sankyo, other from Eli Lilly, other from Taiho, other from Eisai, outside the submitted work; Dr. Morita reports personal fees from AstraZeneca, personal fees from Bristol-Myers Squibb Company, personal fees from Chugai, personal fees from Eisai, personal fees from Eli Lilly, personal fees from MSD, personal fees from Pfizer, personal fees from Taiho, outside the submitted work; Toi M reports grants and personal fees from Chugai, grants and personal fees from Takeda, grants and personal fees from Pfizer, grants and personal fees from Kyowa Kirin, grants and personal fees from C & C Res Lab, grants and personal fees from Taiho, grants from JBCRG association, grants and personal fees from Eisai, grants and personal fees from Daiichi Sankyo, grants and personal fees from AstraZeneca, personal fees from Eli Lilly, personal fees from MSD, personal fees from Genomic Health, personal fees from Novartis, personal fees from Konica Minolta, grants from Astellas, outside the submitted work; and Board of directors; JBCRG association, Organisation for Oncology and Translational Research, Kyoto Breast cancer Research Network. Ohno S reports personal fees from Chugai, grants and personal fees from Eisai, grants and personal fees from Taiho, personal fees from AstraZeneca, personal fees from Pfizer, personal fees from Eli Lilly, personal fees from Kyowa Kirin, personal fees from Nippon Kayaku, outside the submitted work;
: The study was carried out in accordance with the Declaration of Helsinki and the Ethical Guidelines for Clinical Research of the Ministry of Health, Labour and Welfare of Japan. The study protocol, procedures, and consent forms were approved by the institutional review board of each participating institution.
: Written informed consent was obtained from all patients.