Crossmark

Combining traditional 2D and modern physical organic-derived descriptors to predict enhanced enantioselectivity for the key aza-Michael conjugate addition in the synthesis of Prevymis™ (letermovir)

Crossref DOI link: https://doi.org/10.1039/c8sc02089b

Published Online: 2018

Update policy: https://doi.org/10.1039/rsc_crossmark_policy

Authors

Metsänen, Toni T. https://orcid.org/0000-0002-3966-6067
Lexa, Katrina W. https://orcid.org/0000-0001-7163-2302
Santiago, Celine B.

Chung, Cheol K.

Xu, Yingju

Liu, Zhijian

Humphrey, Guy R.

Ruck, Rebecca T. https://orcid.org/0000-0001-9980-9675
Sherer, Edward C. https://orcid.org/0000-0001-8178-9186
Sigman, Matthew S. https://orcid.org/0000-0002-5746-8830
Funding

Funding for this research was provided by:

Division of Chemistry (CHE-1361296)
License Information

Version of Record valid from 2018-07-18
More Information

SIMILARITY CHECK

: This document is Similarity Check deposited

RELATED DATA

: Supplementary Information

IDENTIFIERS

: Toni T. Metsänen (ORCID)

: Toni T. Metsänen (ResearcherID)

: Katrina W. Lexa (ORCID)

: Rebecca T. Ruck (ORCID)

: Edward C. Sherer (ORCID)

: Matthew S. Sigman (ORCID)

PEER REVIEW METHOD

: Single-blind

PUBLICATION HISTORY

: Received 10 May 2018; Accepted 17 July 2018; Accepted Manuscript published 18 July 2018; Advance Article published 25 July 2018; Version of Record published 29 August 2018

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