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Selective JAK3 Inhibitors with a Covalent Reversible Binding Mode Targeting a New Induced Fit Binding Pocket

Crossref DOI link: https://doi.org/10.1016/j.chembiol.2016.10.008

Published Print: 2016-11

Update policy: https://doi.org/10.1016/elsevier_cm_policy

Authors

Forster, Michael

Chaikuad, Apirat

Bauer, Silke M.

Holstein, Julia

Robers, Matthew B.

Corona, Cesear R.

Gehringer, Matthias

Pfaffenrot, Ellen

Ghoreschi, Kamran

Knapp, Stefan

Laufer, Stefan A.
Funding

Funding for this research was provided by:

Canada Foundation for Innovation

Takeda Pharmaceutical Company

Deutsche Forschungsgemeinschaft (SFB TR156)

Genome Canada

Innovative Medicines Initiative

Wellcome Trust (092809/Z/10/Z)

Pfizer

Ontario Genomics Institute

Ontario Ministry of Economic Development and Innovation

Boehringer Ingelheim

Janssen Biotech
License Information

Text and Data Mining valid from 2016-11-01

Text and Data Mining valid from 2016-11-01

Version of Record valid from 2016-10-19
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This article is maintained by: Elsevier

Article Title: Selective JAK3 Inhibitors with a Covalent Reversible Binding Mode Targeting a New Induced Fit Binding Pocket

Journal Title: Cell Chemical Biology

CrossRef DOI link to publisher maintained version: https://doi.org/10.1016/j.chembiol.2016.10.008

Content Type: article

Copyright: © 2016 The Authors. Published by Elsevier Ltd.