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Cryo-EM structures of ASC and NLRC4 CARD filaments reveal a unified mechanism of nucleation and activation of caspase-1

Crossref DOI link: https://doi.org/10.1073/pnas.1810524115

Published Online: 2018-10-02

Published Print: 2018-10-23

Update policy: https://doi.org/10.1073/pnas.cm10313

Authors

Li, Yang

Fu, Tian-Min

Lu, Alvin

Witt, Kristen

Ruan, Jianbin

Shen, Chen

Wu, Hao
Funding

Funding for this research was provided by:

HHS | NIH | National Institute of Allergy and Infectious Diseases (HD087988)

HHS | National Institutes of Health (AI124491)

Harvard Digestive and Disease Center (DK034854)
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Publication History

Published: 2018-10-02