Huo, Xiaochuan https://orcid.org/0000-0003-1264-5132
Ma, Gaoting https://orcid.org/0000-0002-9374-7589
Zhang, Xuelei
Pan, Yuesong https://orcid.org/0000-0003-3082-6789
Tong, Xu https://orcid.org/0000-0002-3277-6941
Sun, Dapeng https://orcid.org/0000-0001-6321-5381
Liu, Liping https://orcid.org/0000-0003-2943-055X
Wang, Yilong https://orcid.org/0000-0002-3267-0039
Liebeskind, David S https://orcid.org/0000-0002-5109-8736
Wang, Yongjun
Pereira, Vitor Mendes
Ren, Zeguang https://orcid.org/0000-0002-7431-2643
Miao, Zhongrong
Clinical trials referenced in this document:
Documents that mention this clinical trial
Select wisely: the ethical challenge of defining large core with perfusion in the early time window
https://doi.org/10.1136/neurintsurg-2021-017386
Number of Passes of Endovascular Therapy for Stroke With a Large Ischemic Core: Secondary Analysis of RESCUE-Japan LIMIT
https://doi.org/10.1161/strokeaha.123.042552
Identifying large ischemic core volume ranges in acute stroke that can benefit from mechanical thrombectomy
https://doi.org/10.1136/neurintsurg-2020-016934
Endovascular therapy in acute anterior circulation large vessel occlusive patients with a large infarct core (ANGEL-ASPECT): protocol of a multicentre randomised trial
https://doi.org/10.1136/svn-2022-001865
Intravenous alteplase before endovascular therapy for acute large vessel occlusion with large ischemic core: subanalysis of a randomized clinical trial
https://doi.org/10.1136/jnis-2023-020846
Expanding the Treatable Imaging Profile in Patients With Large Ischemic Stroke: Subanalysis From a Randomized Clinical Trial
https://doi.org/10.1161/strokeaha.124.046828
Endovascular reperfusion outcomes in patients with a stroke and low ASPECTS is highly dependent on baseline infarct volumes
https://doi.org/10.1136/neurintsurg-2020-017184
Predictors of independent outcome of thrombectomy in stroke patients with large baseline infarcts in clinical practice: a multicenter analysis
https://doi.org/10.1136/neurintsurg-2019-015641
Benefit and risk of intravenous alteplase in patients with acute large vessel occlusion stroke and low ASPECTS
https://doi.org/10.1136/neurintsurg-2021-017986
Documents that mention this clinical trial
Select wisely: the ethical challenge of defining large core with perfusion in the early time window
https://doi.org/10.1136/neurintsurg-2021-017386
Identifying large ischemic core volume ranges in acute stroke that can benefit from mechanical thrombectomy
https://doi.org/10.1136/neurintsurg-2020-016934
Endovascular treatment for large-core ischaemic stroke: a meta-analysis of randomised controlled clinical trials
https://doi.org/10.1136/jnnp-2023-331513
Endovascular therapy in acute anterior circulation large vessel occlusive patients with a large infarct core (ANGEL-ASPECT): protocol of a multicentre randomised trial
https://doi.org/10.1136/svn-2022-001865
About antifragility and the challenge of dealing with endovascular therapy trials that fail to show a positive result
https://doi.org/10.1136/neurintsurg-2019-015564
European Stroke Organisation (ESO) - European Society for Minimally Invasive Neurological Therapy (ESMINT) Guidelines on Mechanical Thrombectomy in Acute Ischemic Stroke
https://doi.org/10.1136/neurintsurg-2018-014569
Effect of age and baseline ASPECTS on outcomes in large-vessel occlusion stroke: results from the HERMES collaboration
https://doi.org/10.1136/neurintsurg-2020-016621
Mechanical thrombectomy in patients with acute ischemic stroke and ASPECTS ≤6: a meta-analysis
https://doi.org/10.1136/neurintsurg-2019-015237
Large core stroke thrombectomy: paradigm shift or futile exercise?
https://doi.org/10.1136/jnis-2023-020219
Cost-effectiveness of endovascular thrombectomy for acute ischemic stroke with established large infarct in Germany: a decision tree and Markov model
https://doi.org/10.1136/jnis-2024-021837
Endovascular reperfusion outcomes in patients with a stroke and low ASPECTS is highly dependent on baseline infarct volumes
https://doi.org/10.1136/neurintsurg-2020-017184
Prediction of 90 day home time among patients with low baseline ASPECTS undergoing endovascular thrombectomy: results from Alberta’s Provincial Stroke Registry (QuICR)
https://doi.org/10.1136/jnis-2022-019064
Predictors of independent outcome of thrombectomy in stroke patients with large baseline infarcts in clinical practice: a multicenter analysis
https://doi.org/10.1136/neurintsurg-2019-015641
Documents that mention this clinical trial
Select wisely: the ethical challenge of defining large core with perfusion in the early time window
https://doi.org/10.1136/neurintsurg-2021-017386
Endovascular therapy in acute anterior circulation large vessel occlusive patients with a large infarct core (ANGEL-ASPECT): protocol of a multicentre randomised trial
https://doi.org/10.1136/svn-2022-001865
Efficacy and safety of bridging therapy and thrombectomy alone in patients with large infarcts of unrestricted size: LASTE trial post hoc analysis
https://doi.org/10.1136/jnis-2025-024872
Effect of workflow metrics on clinical outcomes of low diffusion-weighted imaging Alberta Stroke Program Early Computed Tomography Score (DWI-ASPECTS) patients subjected to mechanical thrombectomy
https://doi.org/10.1136/neurintsurg-2019-015519
Endovascular Thrombectomy in Patients With Largest Baseline Infarcts (ASPECTS 0–2): An Ancillary Analysis of the LASTE Trial
https://doi.org/10.1161/strokeaha.125.054161
Large core stroke thrombectomy: paradigm shift or futile exercise?
https://doi.org/10.1136/jnis-2023-020219
Endovascular reperfusion outcomes in patients with a stroke and low ASPECTS is highly dependent on baseline infarct volumes
https://doi.org/10.1136/neurintsurg-2020-017184
Prediction of 90 day home time among patients with low baseline ASPECTS undergoing endovascular thrombectomy: results from Alberta’s Provincial Stroke Registry (QuICR)
https://doi.org/10.1136/jnis-2022-019064
Does perfusion mismatch modify the benefit of thrombectomy in large core stroke? A meta-analysis of trials
https://doi.org/10.1136/jnis-2025-024351
Clinical outcome of patients with mild pre-stroke morbidity following endovascular treatment: a HERMES substudy
https://doi.org/10.1136/neurintsurg-2021-018428
Documents that mention this clinical trial
Select wisely: the ethical challenge of defining large core with perfusion in the early time window
https://doi.org/10.1136/neurintsurg-2021-017386
Endovascular therapy in acute anterior circulation large vessel occlusive patients with a large infarct core (ANGEL-ASPECT): protocol of a multicentre randomised trial
https://doi.org/10.1136/svn-2022-001865
Effect of age and baseline ASPECTS on outcomes in large-vessel occlusion stroke: results from the HERMES collaboration
https://doi.org/10.1136/neurintsurg-2020-016621
Large core stroke thrombectomy: paradigm shift or futile exercise?
https://doi.org/10.1136/jnis-2023-020219
Endovascular reperfusion outcomes in patients with a stroke and low ASPECTS is highly dependent on baseline infarct volumes
https://doi.org/10.1136/neurintsurg-2020-017184
Endovascular thrombectomy in patients with large core ischemic stroke: a cost-effectiveness analysis from the SELECT study
https://doi.org/10.1136/neurintsurg-2020-016766
Predictors of independent outcome of thrombectomy in stroke patients with large baseline infarcts in clinical practice: a multicenter analysis
https://doi.org/10.1136/neurintsurg-2019-015641
Prediction of 90 day home time among patients with low baseline ASPECTS undergoing endovascular thrombectomy: results from Alberta’s Provincial Stroke Registry (QuICR)
https://doi.org/10.1136/jnis-2022-019064
Benefit and risk of intravenous alteplase in patients with acute large vessel occlusion stroke and low ASPECTS
https://doi.org/10.1136/neurintsurg-2021-017986
Documents that mention this clinical trial
Select wisely: the ethical challenge of defining large core with perfusion in the early time window
https://doi.org/10.1136/neurintsurg-2021-017386
Endovascular therapy in acute anterior circulation large vessel occlusive patients with a large infarct core (ANGEL-ASPECT): protocol of a multicentre randomised trial
https://doi.org/10.1136/svn-2022-001865
Effect of age and baseline ASPECTS on outcomes in large-vessel occlusion stroke: results from the HERMES collaboration
https://doi.org/10.1136/neurintsurg-2020-016621
Endovascular reperfusion outcomes in patients with a stroke and low ASPECTS is highly dependent on baseline infarct volumes
https://doi.org/10.1136/neurintsurg-2020-017184
Cerebral Edema in Patients With Large Ischemic Core After Thrombectomy: A Secondary Analysis of SELECT2 Randomized Trial
https://doi.org/10.1161/strokeaha.125.054015
Prediction of 90 day home time among patients with low baseline ASPECTS undergoing endovascular thrombectomy: results from Alberta’s Provincial Stroke Registry (QuICR)
https://doi.org/10.1136/jnis-2022-019064
Predictors of independent outcome of thrombectomy in stroke patients with large baseline infarcts in clinical practice: a multicenter analysis
https://doi.org/10.1136/neurintsurg-2019-015641
Endovascular thrombectomy in patients with large core ischemic stroke: a cost-effectiveness analysis from the SELECT study
https://doi.org/10.1136/neurintsurg-2020-016766
Association of Ischemic Core Hypodensity With Thrombectomy Treatment Effect in Large Core Stroke: A Secondary Analysis of the SELECT2 Randomized Controlled Trial
https://doi.org/10.1161/strokeaha.124.048899
Sex-Based Differences in Endovascular Thrombectomy Outcomes for Large Ischemic Stroke: A SELECT2 Subanalysis
https://doi.org/10.1161/strokeaha.124.049307
Documents that mention this clinical trial
Predictors of parenchymal hemorrhage after endovascular treatment in large core ischemic stroke: a post-hoc analysis of the ANGEL-ASPECT trial
https://doi.org/10.1136/jnis-2025-023285
Endovascular therapy in acute anterior circulation large vessel occlusive patients with a large infarct core (ANGEL-ASPECT): protocol of a multicentre randomised trial
https://doi.org/10.1136/svn-2022-001865
Endovascular treatment for extracranial internal carotid artery occlusions with large infarcts: ANGEL-ASPECT subanalysis
https://doi.org/10.1136/jnis-2026-024978
Predictors of futile recanalisation in patients with large infarct: a post-hoc analysis of the ANGEL-ASPECT trial
https://doi.org/10.1136/svn-2024-003382
Machine learning models for predicting futile recanalisation after endovascular treatment in patients with large core infarction
https://doi.org/10.1136/svn-2025-004258
A pre-intervention six-item scale for predicting futile recanalization after endovascular therapy in patients with acute ischemic stroke with large core infarction
https://doi.org/10.1136/jnis-2025-023370
Anaesthesia modality on endovascular therapy outcomes in patients with large infarcts: a post hoc analysis of the ANGEL-ASPECT trial
https://doi.org/10.1136/svn-2024-003320
Factors associated with infarct volume growth after mechanical thrombectomy in large core infarction: ANGEL-ASPECT insights
https://doi.org/10.1136/svn-2025-004774
Endovascular reperfusion outcomes in patients with a stroke and low ASPECTS is highly dependent on baseline infarct volumes
https://doi.org/10.1136/neurintsurg-2020-017184
Time-Dependent Impact of Mismatch Profiles on Outcomes Following Endovascular Thrombectomy for Large Ischemic Stroke
https://doi.org/10.1161/strokeaha.125.052698
Clinical Severity and Outcomes in Large Infarcts With Endovascular Therapy: A Post Hoc Analysis of the ANGEL-ASPECT Trial
https://doi.org/10.1161/strokeaha.124.049315
Impact of first pass effect in endovascular treatment of large core stroke: a post-hoc analysis of the ANGEL-ASPECT trial
https://doi.org/10.1136/jnis-2024-021728
Spontaneous recanalization in acute large core ischemic stroke due to large vessel occlusion: a post-hoc analysis of the ANGEL-ASPECT trial
https://doi.org/10.1136/jnis-2024-022357
Sex-Related Differences in Endovascular Treatment Outcomes for Acute Large Infarcts: The ANGEL-ASPECT Subanalysis
https://doi.org/10.1161/strokeaha.124.050025
Effectiveness and safety of bridging therapy and endovascular therapy in patients with large cerebral infarctions: from ANGEL-ASPECT
https://doi.org/10.1136/svn-2024-003120
Funding for this research was provided by:
Covidien Healthcare International Trading
Shanghai HeartCare Medical Technology Co., Ltd
Johnson & Johnson
Genesis MedTech (Shanghai) Co.,Ltd.