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Authors
Abdin, Shifaa M.
Paasch, Daniela https://orcid.org/0009-0002-6857-8784
Kloos, Arnold
Oliveira, Marco Carvalho
Jang, Mi-Sun
Ackermann, Mania
Stamopoulou, Andriana
Mroch, Philipp J
Falk, Christine S
von Kaisenberg, Constantin S
Schambach, Axel
Heuser, Michael
Moritz, Thomas
Hansen, Gesine
Morgan, Michael
Lachmann, Nico https://orcid.org/0000-0002-4245-1497
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Clinical Trials BETA
Clinical trials referenced in this document:
nct04660929 at ClinicalTrials.govDocuments that mention this clinical trial
Engineering macrophages for effective and safe targeting of CD47 cancer cells in the tumor microenvironment
https://doi.org/10.1136/jitc-2025-014457
Constructing the cure: engineering the next wave of antibody and cellular immune therapies
https://doi.org/10.1136/jitc-2025-011761
Targeting tumor-associated macrophages for successful immunotherapy of ovarian carcinoma
https://doi.org/10.1136/jitc-2022-005968
315 Characterization of CT-0508, an anti-HER2 chimeric antigen receptor macrophage (CAR-M), manufactured from patients enrolled in the phase 1, first in human, clinical trial of CT-0508
https://doi.org/10.1136/jitc-2022-sitc2022.0315
A phase 1, first-in-human (FIH) study of autologous macrophages engineered to express an anti-HER2 chimeric antigen receptor (CAR) in participants (pts) with HER2-overexpressing solid tumors.
https://doi.org/10.1200/jco.2023.41.16_suppl.tps2666
Adoptively transferred macrophages for cancer immunotherapy
https://doi.org/10.1136/jitc-2024-010437
CARs and beyond: tailoring macrophage-based cell therapeutics to combat solid malignancies
https://doi.org/10.1136/jitc-2021-002741
Scalable generation of functional human iPSC-derived CAR-macrophages that efficiently eradicate CD19-positive leukemia
https://doi.org/10.1136/jitc-2023-007705
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Funding
Funding for this research was provided by:
European Research Council (101100859 852178)
REBIRTH Research Center for Translational Regenerative Medicine “Förderung aus Mitteln des Niedersächsischen Vorab” (ZN3340)
DFG, German Research Foundation (390874280 EXC 2155)
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