Jeong, Hyein
Koh, Jaemoon
Kim, Sehui
Yim, Jeemin
Song, Seung Geun
Kim, Hanbyeol
Li, Yingying
Lee, Soo Hyun
Chung, Yeon Kyu
Kim, Hongsoon
Lee, Chul-Hwan
Kim, Hye Young
Keam, Bhumsuk https://orcid.org/0000-0002-2974-675X
Lee, Se-Hoon
Chung, Doo Hyun
Jeon, Yoon Kyung https://orcid.org/0000-0001-8466-9681
Clinical trials referenced in this document:
Documents that mention this clinical trial
Use of a bDMARD or tsDMARD for the management of inflammatory arthritis under checkpoint inhibitors: an observational study
https://doi.org/10.1136/rmdopen-2022-002612
Cell-intrinsic PD-L1 signaling drives immunosuppression by myeloid-derived suppressor cells through IL-6/Jak/Stat3 in PD-L1-high lung cancer
https://doi.org/10.1136/jitc-2024-010612
C reactive protein impairs adaptive immunity in immune cells of patients with melanoma
https://doi.org/10.1136/jitc-2019-000234
Insights from immuno-oncology: the Society for Immunotherapy of Cancer Statement on access to IL-6-targeting therapies for COVID-19
https://doi.org/10.1136/jitc-2020-000878
Host response to immune checkpoint inhibitors contributes to tumor aggressiveness
https://doi.org/10.1136/jitc-2020-001996
Increased interleukin-6/C-reactive protein levels are associated with the upregulation of the adenosine pathway and serve as potential markers of therapeutic resistance to immune checkpoint inhibitor-based therapies in non-small cell lung cancer
https://doi.org/10.1136/jitc-2023-007310
Interleukin-6 receptor blockade with tocilizumab to reduce immune-related toxicity with ipilimumab and nivolumab in metastatic melanoma.
https://doi.org/10.1200/jco.2024.42.16_suppl.9538
Circulating tumour cell clusters: isolation, biological significance and therapeutic implications
https://doi.org/10.1136/bmjonc-2024-000437
Selective immune suppression using interleukin-6 receptor inhibitors for management of immune-related adverse events
https://doi.org/10.1136/jitc-2023-006814
Predictive and pharmacodynamic biomarkers for combination therapy in stage III-IV melanoma: A Simon phase II trial (NCT03999749).
https://doi.org/10.1200/jco.2024.42.23_suppl.222
816 Selective immune suppression using interleukin-6 blockade in immune related adverse events
https://doi.org/10.1136/jitc-2021-sitc2021.816
Serum interleukin-6 and C-reactive protein are associated with survival in melanoma patients receiving immune checkpoint inhibition
https://doi.org/10.1136/jitc-2020-000842
On the use of immune checkpoint inhibitors in patients with viral infections including COVID-19
https://doi.org/10.1136/jitc-2020-001145
Documents that mention this clinical trial
Decoding resistance to immune checkpoint inhibitors in non-small cell lung cancer: a comprehensive analysis of plasma proteomics and therapeutic implications
https://doi.org/10.1136/jitc-2024-011427
Cell-intrinsic PD-L1 signaling drives immunosuppression by myeloid-derived suppressor cells through IL-6/Jak/Stat3 in PD-L1-high lung cancer
https://doi.org/10.1136/jitc-2024-010612
COLAR: open-label clinical study of IL-6 blockade with tocilizumab for the treatment of immune checkpoint inhibitor-induced colitis and arthritis
https://doi.org/10.1136/jitc-2022-005111
Phase II trial of weekly or bi-weekly tocilizumab with ipilimumab and nivolumab in advanced melanoma: Clinical outcomes and biomarker analysis.
https://doi.org/10.1200/jco.2024.42.16_suppl.9553
Potential therapies for immune-related adverse events associated with immune checkpoint inhibition: from monoclonal antibodies to kinase inhibition
https://doi.org/10.1136/jitc-2021-003551
Selective immune suppression using interleukin-6 receptor inhibitors for management of immune-related adverse events
https://doi.org/10.1136/jitc-2023-006814
816 Selective immune suppression using interleukin-6 blockade in immune related adverse events
https://doi.org/10.1136/jitc-2021-sitc2021.816
Steroid-sparing strategies for managing immune-related adverse events
https://doi.org/10.1136/jitc-2025-013776
Documents that mention this clinical trial
Decoding resistance to immune checkpoint inhibitors in non-small cell lung cancer: a comprehensive analysis of plasma proteomics and therapeutic implications
https://doi.org/10.1136/jitc-2024-011427
Cell-intrinsic PD-L1 signaling drives immunosuppression by myeloid-derived suppressor cells through IL-6/Jak/Stat3 in PD-L1-high lung cancer
https://doi.org/10.1136/jitc-2024-010612
Increased interleukin-6/C-reactive protein levels are associated with the upregulation of the adenosine pathway and serve as potential markers of therapeutic resistance to immune checkpoint inhibitor-based therapies in non-small cell lung cancer
https://doi.org/10.1136/jitc-2023-007310
COLAR: open-label clinical study of IL-6 blockade with tocilizumab for the treatment of immune checkpoint inhibitor-induced colitis and arthritis
https://doi.org/10.1136/jitc-2022-005111
Funding for this research was provided by:
Ministry of Trade, Industry and Energy (MOTIE), Republic of Korea (10067758)
Seoul National University, Cancer Research Institute Research Program (0431-20220017)
Korean Association for Lung Cancer (KALC-202312)
Health Fellowship Foundation, Repblic of Korea (N/A)
National Research Foundation of Korea (NRF), Republic of Korea (2020R1A4A1017515)
National Research Foundation of Korea (NRF), Republic of Korea (RS-2023-00217571)
National Research Foundation of Korea (NRF), Republic of Korea (RS-2023-00252806)
Ministry of Science and ICT, Republic of Korea (2020R1A2C3006535)
Ministry of Science and ICT, Republic of Korea (2020R1F1A1070825)