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Authors
Ninmer, Emily K https://orcid.org/0009-0001-2973-9883
Petroni, Gina R
Gastman, Brian R
Gaughan, Elizabeth M
Isaacs, James M
Haden, Kathleen
Kaur, Varinder
Wages, Nolan A
Chianese-Bullock, Kimberly A
Smith, Kelly T
Wright, Paul
Bryant, Jennifer
Dunlap-Brown, Marya
Engel, Jack A
Bekiranov, Stefan
Mauldin, Ileana S
Truong, Thach-Giao
Bullock, Timothy N J https://orcid.org/0000-0001-6141-3261
Slingluff, Craig L Jr. https://orcid.org/0000-0002-6664-4373
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Clinical Trials BETA
Clinical trials referenced in this document:
nct04364230 at ClinicalTrials.govnct04364230 at ClinicalTrials.govDocuments that mention this clinical trial
CD40×HER2 bispecific antibody overcomes the CCL2-induced trastuzumab resistance in HER2-positive gastric cancer
https://doi.org/10.1136/jitc-2022-005063
Phase I/II clinical trial of a melanoma vaccine targeting shared non-mutated antigens and a shared mutated BRAF neoantigen with an agonistic CD40 antibody (CDX-1140) plus TLR3 agonist (poly-ICLC)
https://doi.org/10.1136/jitc-2025-013613
nct04364230 at ClinicalTrials.govDocuments that mention this clinical trial
CD40×HER2 bispecific antibody overcomes the CCL2-induced trastuzumab resistance in HER2-positive gastric cancer
https://doi.org/10.1136/jitc-2022-005063
Phase I/II clinical trial of a melanoma vaccine targeting shared non-mutated antigens and a shared mutated BRAF neoantigen with an agonistic CD40 antibody (CDX-1140) plus TLR3 agonist (poly-ICLC)
https://doi.org/10.1136/jitc-2025-013613
Documents that mention this clinical trial
CD40×HER2 bispecific antibody overcomes the CCL2-induced trastuzumab resistance in HER2-positive gastric cancer
https://doi.org/10.1136/jitc-2022-005063
Phase I/II clinical trial of a melanoma vaccine targeting shared non-mutated antigens and a shared mutated BRAF neoantigen with an agonistic CD40 antibody (CDX-1140) plus TLR3 agonist (poly-ICLC)
https://doi.org/10.1136/jitc-2025-013613
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Funding
Funding for this research was provided by:
UVA Cancer Center (Rebecca Harris Fellowship (EKN))
Philanthropic Gift (Alice and Bill Goodwin)
National Institutes of Health (2P30 CA044579)
U.S. Department of Defense (Translational Team Science Award CA181046)
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