Thool, Madhuri
Sudhagar, S.
Thummer, Rajkumar P.
Chapter History
First Online: 29 August 2023
Declarations
: None.
: The purification of HTN-NANOG fusion protein from <i>E. coli</i> with a retained secondary structure and its bioactivity in human cells is demonstrated in this study. This study reported that human NANOG fusion protein enhanced proliferation, migration and downregulated p27 gene expression in HeLa cells, demonstrating its bioactivity. This biologically active human NANOG protein can be utilized to elucidate the biological function of NANOG in various cellular processes associated with cancer and induced pluripotent stem cells.
Conference Information
Conference Acronym: NERC
Conference Name: North-East Research Conclave
Conference City: Guwahati
Conference Country: India
Conference Year: 2022
Conference Start Date: 20 May 2022
Conference End Date: 22 May 2022
Conference ID: nerc2022
Conference URL: https://www.iitg.ac.in/rnd/nerc/