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Non-peptidyl small molecule, adenosine, 5′-Se-methyl-5′-seleno-, 2′,3′-diacetate, activates insulin receptor and attenuates hyperglycemia in type 2 diabetic Leprdb/db mice

Crossref DOI link: https://doi.org/10.1007/s00018-019-03249-4

Published Online: 2019-08-05

Published Print: 2020-04

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Lan, Zi-Jian https://orcid.org/0000-0002-5904-6834
Lei, Zhenmin

Yiannikouris, Alexandros

Yerramreddy, Thirupathi Reddy

Li, Xian

Kincaid, Hayley

Eastridge, Katie

Gadberry, Hannah

Power, Chloe

Xiao, Rijin

Lei, Lei

Seale, Olivia

Dawson, Karl

Power, Ronan
Funding

Funding for this research was provided by:

Life Sciences Research Program of Alltech Inc
License Information

Text and Data Mining valid from 2019-08-05

Version of Record valid from 2019-08-05
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Article History

Received: 6 February 2019

Revised: 5 July 2019

Accepted: 23 July 2019

First Online: 5 August 2019

Compliance with ethical standards

:

: ZJL, AY, TRY, HK, KE, RX, KW and RP are current employees of Alltech, Inc. HG, CP and OL are previous visiting scholars at Alltech, Inc. Alltech, Inc. has filed a patent application for this study (US patent application number PCT/US18/30371). ZL, XL and LL have no conflict of interest.

: We declare that the experiments comply with the current laws of the United States of America.

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