Document is current

Article History

Received: 18 January 2019

Revised: 24 July 2019

Accepted: 25 July 2019

First Online: 1 August 2019

Compliance with ethical standards

:

: The authors declare that they have no conflict of interest.

: All animals received humane care. All experiments with mice were performed according to the National/EU Guidelines for the Care and Use of Laboratory Animals in Research and the approval of the Ethics Committee of the Spanish National Research Council (CSIC, file JMPV.1.14/CEEA). All experiments with frogs were approved by the Ethical Committee for the Use of Laboratory Animals of the University of Salamanca in agreement with the criteria outlined in the “Guide for the Care and Use of Laboratory Animals” prepared by the National Academy of Sciences and published by the National Institutes of Health (NIH publication vol 2, 2nd Ed, 2002).