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Targeting lactate dehydrogenase B-dependent mitochondrial metabolism affects tumor initiating cells and inhibits tumorigenesis of non-small cell lung cancer by inducing mtDNA damage

Crossref DOI link: https://doi.org/10.1007/s00018-022-04453-5

Published Online: 2022-07-25

Published Print: 2022-08

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Deng, Haibin

Gao, Yanyun

Trappetti, Verdiana

Hertig, Damian

Karatkevich, Darya

Losmanova, Tereza

Urzi, Christian

Ge, Huixiang

Geest, Gerrit Adriaan

Bruggmann, Remy

Djonov, Valentin

Nuoffer, Jean-Marc

Vermathen, Peter

Zamboni, Nicola

Riether, Carsten

Ochsenbein, Adrian

Peng, Ren-Wang

Kocher, Gregor Jan

Schmid, Ralph Alexander

Dorn, Patrick

Marti, Thomas Michael https://orcid.org/0000-0003-3005-220X
Funding

Funding for this research was provided by:

Krebsliga Schweiz (KFS-5405-08-2021-R)

University of Bern
License Information

Text and Data Mining valid from 2022-07-25

Version of Record valid from 2022-07-25
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Article History

Received: 18 January 2022

Revised: 21 June 2022

Accepted: 27 June 2022

First Online: 25 July 2022

Declarations

:

: The authors declare that they have no competing interests.

: Not applicable.

: Mouse studies were conducted in accordance with Institutional Animal Care and Ethical Committee-approved animal guidelines and protocols.

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