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Heterocomplexes between the atypical chemokine MIF and the CXC-motif chemokine CXCL4L1 regulate inflammation and thrombus formation

Crossref DOI link: https://doi.org/10.1007/s00018-022-04539-0

Published Online: 2022-09-12

Published Print: 2022-10

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Brandhofer, Markus https://orcid.org/0000-0002-1629-8353
Hoffmann, Adrian

Blanchet, Xavier https://orcid.org/0000-0001-7936-3848
Siminkovitch, Elena

Rohlfing, Anne-Katrin https://orcid.org/0000-0001-5469-3648
El Bounkari, Omar https://orcid.org/0000-0002-3051-2096
Nestele, Jeremy A.

Bild, Alexander

Kontos, Christos

Hille, Kathleen

Rohde, Vanessa

Fröhlich, Adrian

Golemi, Jona

Gokce, Ozgun

Krammer, Christine

Scheiermann, Patrick https://orcid.org/0000-0001-7334-3096
Tsilimparis, Nikolaos

Sachs, Nadja

Kempf, Wolfgang E.

Maegdefessel, Lars

Otabil, Michael K.

Megens, Remco T. A. https://orcid.org/0000-0001-9871-6696
Ippel, Hans

Koenen, Rory R. https://orcid.org/0000-0002-9955-9730
Luo, Junfu

Engelmann, Bernd

Mayo, Kevin H.

Gawaz, Meinrad

Kapurniotu, Aphrodite

Weber, Christian https://orcid.org/0000-0003-4610-8714
von Hundelshausen, Philipp

Bernhagen, Jürgen https://orcid.org/0000-0003-2996-2652
Funding

Funding for this research was provided by:

Deutsche Forschungsgemeinschaft (SFB1123-A3, SFB1123-A3, SFB1123-A2, SFB1123-A1, SFB1123-Z1, SFB1123-B5, SFB240-B01 (374031971 – TRR 240), DFG INST 409/209-1 FUGG, EXC 2145 SyNergy—ID 390857198, EXC 2145 SyNergy—ID 390857198, EXC 2145 SyNergy—ID 390857198, SFB1123-B6)

Medizinischen Fakultät, Ludwig-Maximilians-Universität München (Metiphys scholarship of LMU Munich, FöFoLe)

Friedrich-Baur-Stiftung (AH2020)

Universitätsklinik München
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Text and Data Mining valid from 2022-09-12

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Article History

Received: 28 January 2022

Revised: 31 July 2022

Accepted: 22 August 2022

First Online: 12 September 2022

Declarations

:

: J.B., P.v.H., C.K., O.E.B., C.W., and A.K. are inventors on patent applications related to anti-MIF and anti-chemokine strategies in inflammatory and cardiovascular diseases. The other authors declare that they have no competing interests.

: Mouse maintenance and experiments were reviewed and overseen by the institutional animal use and care committee of the local authorities (Regierung von Oberbayern, ROB, Germany) and performed in accordance with the procedures provided by the animal protection representative of CSD. Human thrombus tissue specimens were obtained as disposable material from vascular surgery procedures under ethics allowance LMU Munich 18-104 and TUM-MRI project # 2799/10).

: N/A.

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