Jooss, Natalie J.
Diender, Marije G.
Fernández, Delia I.
Huang, Jingnan
Heubel-Moenen, Floor C. J.
van der Veer, Arian
Kuijpers, Marijke J. E.
Poulter, Natalie S.
Henskens, Yvonne M. C.
te Loo, Maroeska
Heemskerk, Johan W. M. http://orcid.org/0000-0002-2848-5121
Funding for this research was provided by:
HORIZON EUROPE Marie Sklodowska-Curie Actions (766118)
Article History
Received: 14 July 2023
Revised: 15 October 2023
Accepted: 21 November 2023
First Online: 18 January 2024
Declarations
:
: J.W.M.H. is a consultant at Synapse Research Institute. The other authors declare no relevant conflict of interest.
: Blood donors gave informed consent according to the declaration of Helsinki to participate in the study. Approval was obtained from the medical ethics committee from Maastricht University Medical Centre<sup>+</sup> (MUMC<sup>+</sup>, code: 2017–0285). Permission of blood drawing from Noonan patients was obtained from the Medical Ethics Committees of Radboud University (Evaluation of Bleeding Disorders in Noonan Patients, non-WMO) and MUMC<sup>+</sup> (ProBe-AHP: Predictors of Bleeding Evaluation in Adult Hematologic Patients with Bleeding Tendencies, METC 14–4-036, Dutch Trial Register, NL9643). The ethical permission did not allow disclosure of subject characteristics other than indicated.
: All authors have read the manuscript and agree with submission for publication.