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Intervertebral disc-intrinsic Hedgehog signaling maintains disc cell phenotypes and prevents disc degeneration through both cell autonomous and non-autonomous mechanisms

Crossref DOI link: https://doi.org/10.1007/s00018-023-05106-x

Published Online: 2024-02-03

Published Print: 2024-12

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Zhang, Lei

Hu, Siyuan

Xiu, Chunmei

Li, Meng

Zheng, Yixin

Zhang, Rui

Li, Bin

Chen, Jianquan https://orcid.org/0000-0002-0468-6287
Funding

Funding for this research was provided by:

National Natural Science Foundation of China (82272543, 81772294, 81974344)
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Article History

Received: 13 November 2023

Revised: 18 December 2023

Accepted: 22 December 2023

First Online: 3 February 2024

Declarations

:

: The authors have no relevant financial or non-financial interests to disclose.

: The procedures regarding animal handling were authorized by the Ethics Committee of Soochow University and conducted in accordance with the Guide for the Care and Use of Laboratory animals developed by the National Institutes of Health in USA. This study did not involve human subjects.

: Not applicable. This manuscript does not contain any unauthorized data.

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