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Glucose metabolite methylglyoxal induces vascular endothelial cell pyroptosis via NLRP3 inflammasome activation and oxidative stress in vitro and in vivo

Crossref DOI link: https://doi.org/10.1007/s00018-024-05432-8

Published Online: 2024-09-13

Published Print: 2024-12

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Wang, Yanan

Chen, Jinxiang

Zheng, Youkun

Jiang, Jun

Wang, Liqun

Wu, Jianbo

Zhang, Chunxiang

Luo, Mao https://orcid.org/0000-0002-9076-7875
Funding

Funding for this research was provided by:

National Natural Science Foundation of China (82370419)

National Natural Science Foundation of China (81800434)

National Natural Science Foundation of China (82030007)

Sichuan Province Science and Technology Support Program (2022YFS0627)

Luzhou Science and Technology Bureau (2023SYF103)
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Text and Data Mining valid from 2024-09-13

Version of Record valid from 2024-09-13
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Article History

Received: 6 May 2024

Revised: 21 August 2024

Accepted: 28 August 2024

First Online: 13 September 2024

Declarations

:

: The authors declare that they have no conflict of interest regarding the publication of this article. Figures were created with Bio Render software. Cbiorender.com.

: All animal procedures were approved and performed under the supervision of the Institutional Animal Care and Use Committee (IACUC) at Southwest Medical University, China.

: Not applicable.

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