Chen, Hui
Zhang, Xuemei
Wang, Ziyi
Luo, Jing
Liu, Yingbin
Shao, Rong https://orcid.org/0009-0002-1567-9629
Funding for this research was provided by:
National Natural Science Foundation of China (81772512)
Science and Technology Innovation Plan Of Shanghai Science and Technology Commission (20S11901700)
Xinhua Hospital Incubation grant (17DZ2260200)
Article History
Received: 9 July 2024
Revised: 11 October 2024
Accepted: 28 October 2024
First Online: 24 December 2024
Declarations
:
: The study on human samples was approved by the Ethics Committee internal review board of Shanghai General Hospital (affiliated to Shanghai Jiao Tong University). All animal experiments were approved by the Institutional Animal Care and Use Committee of Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine.
: The authors affirm that human research participants provided informed consent for publication of the images in Figs. I–K; G, J, K; A, B; , Tables , .
: tumor KP, IDO1/TDO2-mediated KP metabolism, tumor immune microenvironment, cellular collaboration between tumor cells and macrophages, CD8+ T cell immunity.
: The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.