Sun, Fangyuan
Chen, Yiting
Li, Yuanyuan
Zhang, Shucai
Yu, Ting
Jiang, Mingyan
Jiang, Aifang
Ren, Chune
Zhong, Xiaoyan
Jeong, Jae-Wook
Yang, Tingting https://orcid.org/0000-0001-9927-3057
Funding for this research was provided by:
Qilu Health and Health Leading Talent Cultivation Project (ZR2022QC200)
Natural Science Foundation of Shandong Province (ZR2021MH235)
Shandong province college science and technology plan project (J17KA254)
Clinical Research Center of Affiliated Hospital of Weifang Medical University (2021wyfylcyj01)
Medical Research Cultivation Fund Project of Affiliated Hospital of Weifang Medical University (2021wyfyzzjj10)
Weifang Youth Medical Talent Support Project (Weifang Youth Medical Talent Support Project)
Graduate Student Research Grant of Shandong Second Medical University (2024YJSCX009)
Article History
Received: 10 April 2025
Revised: 25 July 2025
Accepted: 31 August 2025
First Online: 27 December 2025
Declarations
:
: The procedures related to human tissues were approved by the Medical Research Ethics Review Committee of Shandong Second Medical University Affiliated Hospital (Ethics number: 2024YX097). Animal experiments were performed according to the National Institutes of Health’s Guide for the Care and Use of Laboratory Animals and were approved by the Experimental Animals Ethics Review Committee of Shandong Second Medical University (Ethics number: 2024SDL204).
: All authors consent to the publication of the article.
: Informed consent was obtained from all patients for being included in the study.
: The authors declare that they have no conflicts of interest.