Thomas-Rüddel, Daniel O. http://orcid.org/0000-0001-9143-8566
Fröhlich, Holger
Schwarzkopf, Daniel
Bloos, Frank
Riessen, Reimer
Funding for this research was provided by:
Bundesministerium für Bildung und Forschung (FKZ 01EO1002)
Universitätsklinikum Jena
Article History
Received: 17 January 2023
Revised: 5 May 2023
Accepted: 3 June 2023
First Online: 28 June 2023
Declarations
:
: D.O. Thomas-Rüddel, H. Fröhlich, D. Schwarzkopf, F. Bloos and R. Riessen declare that they have no competing interests.
: The study was approved by the ethics committee of the medical faculty of the Eberhard-Karls-University Tubingen (104/2015BO2, 20 April 2015, original study title “Einfluss von Komorbiditäten auf die Mortalität bei internistischen Intensivpatienten mit schwerer Sepsis und septischem Schock”). Due to the observational nature of the study the need for informed consent was waived by the ethics committee and the data security officer of the university hospital. The multicenter study (MEDUSA) whose database was partially used was approved locally by the ethics committee of the medical faculty of the Eberhard-Karls-University Tubingen (556/2010BO2, 13 December 2010, original study title “Medical Education for Sepsis Source Control and Antibiotics (MEDUSA)”) and overall by the ethics committee of the university hospital Jena (2910–08/10, 30 November 2010, original study title “Medical Education for Sepsis Source Control and Antibiotics (MEDUSA)”) and it was registered at ClinicalTrials.gov (NCT01187134). The need for informed consent for the MEDUSA trial was waived by all involved institutional review boards and all responsible state data protection boards.