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Article History

Received: 19 October 2025

Revised: 16 December 2025

Accepted: 28 December 2025

First Online: 19 January 2026

Declarations

: The manuscript submitted represents our own original work and has not been published and is not being submitted or considered for publication elsewhere. All authors participated in the work in a substantive way and are prepared to take public responsibility for the work. The text, illustrations, and any other materials included in the manuscript do not infringe upon any existing copyright or other rights of anyone. The authors are agreeing that all materials submitted for evaluation (including text, figures, etc.) retains the property/copyrights of The Science of Nature. In the case of not acceptable papers, after their rejection the property of all materials will backward to the authors. Reproduction, posting, transmission or other distribution or use of the article or any material contained therein, requires a citation to the journal The Science of Nature.

: The study protocol was approved by the Animal Ethical Committee of the Institute of Bioorganic Chemistry, AS RUz (Protocol No: 133/1a/h; approved on August 4, 2014).

: The authors declare no competing interests.