Tarry-Adkins, Jane L. http://orcid.org/0000-0001-9569-6132
Robinson, India G.
PantaleĆ£o, Lucas C. http://orcid.org/0000-0002-5626-8810
Armstrong, Jenna L.
Thackray, Benjamin D.
Holzner, Lorenz M. W.
Knapton, Alice E.
Virtue, Sam http://orcid.org/0000-0002-9545-5432
Jenkins, Benjamin
Koulman, Albert http://orcid.org/0000-0001-9998-051X
Murray, Andrew J. http://orcid.org/0000-0002-0929-9315
Ozanne, Susan E. http://orcid.org/0000-0001-8753-5144
Aiken, Catherine E. http://orcid.org/0000-0002-6510-5626
Funding for this research was provided by:
Evelyn Trust (16/33)
NIHR Cambridge Biomedical Research Centre (146281)
Medical Research Council (MC_UU_00014/4, MR/T016701/1)
Gates Foundation
Wellcome Trust (220033/Z/19/Z)
British Heart Foundation (FS/19/54/34889C, FS/4yPhD/F/20/34124C, PG/20/11/34957, RG/17/12/33167)
Article History
Received: 17 April 2023
Accepted: 18 July 2023
First Online: 5 September 2023
Data availability
: Data are available upon request to the corresponding author.
: This research was funded by a Medical Research Council New Investigator Grant (MR/T016701/1) to CEA. CEA, BJ and AK are supported by the NIHR Cambridge Biomedical Research Centre (146281). The views expressed are those of the author(s) and not necessarily those of the NIHR or the Department of Health and Social Care. SEO is supported by the Medical Research Council (MC_UU_00014/4) and the British Heart Foundation (RG/17/12/33167 and PG/20/11/34957). AJM is supported by the Evelyn Trust (16/33), Gates Foundation, British Heart Foundation (FS/4yPhD/F/20/34124C and FS/19/54/34889C) and Wellcome Trust (220033/Z/19/Z).
: The authors declare that there are no relationships or activities that might bias, or be perceived to bias, their work.
: CEA, SEO, AJM, IGR and AK were responsible for conception and design of the experiments. JLT-A, IGR, LCP, JLA, BDT, LMWH, AEK, SV and BJ performed experiments. CEA, SEO, AJM, IGR, AK and BJ analysed and interpreted the data. CEA and JLT-A drafted the manuscript. All authors critically evaluated and discussed the manuscript. All authors approved the final version. CEA designed experiments, contributed to discussion, analysed and interpreted the data, and wrote and critically evaluated the manuscript. CEA is the guarantor of this work and, as such, had full access to all the data in the study and takes responsibility for the integrity of the data and the accuracy of the data analysis and controlled the decision to publish.