Gao, Lei
Ramirez, Francisco J.
Cabrera, Jody Tori O.
Varghese, Mathews V.
Watanabe, Makiko
Tsuji-Hosokawa, Atsumi
Zheng, Qiuyu
Yang, Mingya
Razan, Md Rahatullah
Kempf, Carrie L.
Camp, Sara M.
Wang, Jian
Garcia, Joe G. N.
Makino, Ayako http://orcid.org/0000-0003-1259-8604
Funding for this research was provided by:
National Heart, Lung, and Blood Institute (HL126609, HL141387, HL142214, HL146764)
Congressionally Directed Medical Research Programs (W81XWH2110472)
Article History
Received: 9 January 2024
Accepted: 25 April 2024
First Online: 19 June 2024
Data availability
: All data in the current study are available from the corresponding author upon reasonable request.
: This work was supported by grants from the Department of Defense (W81XWH2110472 to AM) and from the National Heart, Lung and Blood Institute of the NIH (HL146764 to AM, HL142214 to AM, HL141387 to JGNG and HL126609 to JGNG). The RNA-seq performed by the UCSD IGM Genomics Center utilised an Illumina NovaSeq 6000 that was purchased with funding from NIH shared instrument grant (SIG) grant #S10OD026929. The UCSD CCBB is supported by Altman Clinical and Translational Research Institute grant #UL1TR001442. The Visual Sonics Vevo F2 system was purchased with the NIH SIG grant #S10OD032268.
: JGNG is the CEO and Founder of Aqualung Therapeutics. All other authors declare that there are no relationships or activities that might bias, or be perceived to bias, their work.
: LG, FJR and JTOC designed the research studies, conducted the experiments, analysed the data and drafted and reviewed the manuscript. MVV, MW, AT-H, QZ, MY, MRR, CLK and SMC performed the experiments, analysed data and reviewed the manuscript. JW and JGNG contributed to the analysis and interpretation of data and reviewed the manuscript. AM conceived the project, designed the experiments, analysed the data and wrote the manuscript. LG, FJR and JTOC contributed equally to this work. All authors reviewed and approved the version to be published. AM is the guarantor of this work, and, as such, has full access to all the data in the study and takes responsibility for the integrity of the data and the accuracy of the data analysis.