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Authors
Yamaguchi, Muneo
Nakao, Shintaro https://orcid.org/0000-0003-4200-0052
Arima, Mitsuru
Little, Karis
Singh, Aditi
Wada, Iori
Kaizu, Yoshihiro
Zandi, Souska
Garweg, Justus G.
Matoba, Tetsuya
Shiraishi, Wataru
Yamasaki, Ryo
Shibata, Kensuke
Go, Yasuhiro
Ishibashi, Tatsuro
Uemura, Akiyoshi
Stitt, Alan W.
Sonoda, Koh-Hei
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Funding
Funding for this research was provided by:
JSPS KAKENHI (17K11456)
JSPS KAKENHI (20K09829)
JSPS KAKENHI (21K16897)
Takeda Science Foundation
Bayer Retina Award
The Charitable Trust Fund for Ophthalmic Research in Commemoration of Santen Pharmaceutical’s Founder
Alcon Pharma Research Grants
The Foundation for The Advancement of Clinical Medicine
Novartis Pharma Research Grants
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Article History
Received: 11 February 2024
Accepted: 30 April 2024
First Online: 8 July 2024
Acknowledgements
: We thank M. Kurata and T. Iwasaki (Kyushu University) for technical assistance.
: The data generated and presented in the present study are available from the corresponding author on reasonable request.
: This study was supported by grants from JSPS KAKENHI (no. 17K11456 and no. 20K09829 to SN; no. 21K16897 to MY), the Charitable Trust Fund for Ophthalmic Research in Commemoration of Santen Pharmaceutical’s Founder (SN), Bayer Retina Award (SN), Novartis Pharma Research Grants (SN), Alcon Pharma Research Grants (SN), Takeda Science Foundation (SN), The Foundation for The Advancement of Clinical Medicine, Fukuoka, Japan (SN) and grants from Kowa Company, Ltd.
: SN and K-HS received research support fees from Kowa Company, Ltd. Kyushu University and Kowa Company, Ltd. have patents (patent no. 6860884 and no. EP3626245) related to software that quantifies HRF from en face OCT images and ripasudil as a therapeutic agent for ocular fundus disease, respectively. MA has received materials from Kowa Co., Ltd., used in a separate clinical trial (NCT04621136). The other authors declare that there are no relationships or activities that might bias, or be perceived to bias, their work.
: MY conceived the project, designed the experiments, acquired the data, analysed the data and drafted the manuscript. MA, IW, YK, WS, RY, KS and YG performed the experiments, collected data, analysed and interpreted data, and reviewed the manuscript. KL, AS, SZ and JGG acquired the data, were involved in the analysis of the data and reviewed the manuscript. TM designed the experiments and was involved in the interpretation of the data and reviewed the manuscript. AU and AWS interpreted data and wrote/revised the manuscript. TI and K-HS interpreted data and revised the manuscript. SN conceived the project, designed the experiments, acquired the data, analysed the data and wrote the manuscript. All the authors approved the final version of the manuscript to be published. SN is the guarantor of this work and, as such, had full access to all the data in the study and takes responsibility for the integrity of the data and the accuracy of the data analysis.
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