Dunne, Fidelma
Newman, Christine
Alvarez-Iglesias, Alberto
O’Shea, Paula
Devane, Declan
Gillespie, Paddy
Egan, Aoife
O’Donnell, Martin
Smyth, Andrew
Funding for this research was provided by:
Health Research Board Ireland
National University Ireland, Galway
Article History
Received: 10 May 2024
Accepted: 12 July 2024
First Online: 31 August 2024
Data availability
: Data are not available as ongoing and long-term follow-up is underway.
: Open Access funding provided by the IReL Consortium. The trial was funded by the Health Research Board of Ireland (HRB), coordinated by the HRB-Clinical Research Facility Galway. The funders had no role in the study design, data collection and analysis, decision to publish or preparation of the manuscript.
: The authors received non-financial support from Merck Healthcare KGaA and Ascensia, which contributed metformin and matched placebo and blood glucose monitoring strips, respectively.
: FD, AE, AS, DD and MOD devised the concept for this trial and FD, AE, CN, AS, DD, PO’S and MO’D wrote the protocol. AA-I and PG performed the statistical analysis. All authors drafted and revised the manuscript and approved the final version to be published. FD and CN are accountable for the integrity of the work as a whole.