Heikkilä, Tea E. https://orcid.org/0009-0008-6892-3692
Kaiser, Emilia K. https://orcid.org/0009-0004-1917-3777
Lin, Jake https://orcid.org/0000-0001-9928-1663
Gill, Dipender https://orcid.org/0000-0001-7312-7078
Koskenniemi, Jaakko J. https://orcid.org/0000-0002-9348-3325
Karhunen, Ville https://orcid.org/0000-0001-6064-1588
Article History
Received: 19 February 2024
Accepted: 11 July 2024
First Online: 13 September 2024
Acknowledgements
: The authors wish to acknowledge CSC – IT Center for Science, Finland, for computational resources, the authors of original studies for summary statistics, T. Kinnunen (University of Eastern Finland) for helpful discussions, and two anonymous reviewers for insightful comments.During the preparation of this work the authors used ChatGPT version 4.0 to proofread and to improve the readability of the manuscript. After using this tool/service, the authors reviewed and edited the content as needed and take full responsibility for the content of the publication.
: Analysis code can be accessed at , which also includes instructions on how to download the original GWAS summary statistics.
: This study was funded by Kyllikki ja Uolevi Lehikoisen säätiö, Foundation for Paediatric Research, Finnish Cultural Foundation, JDRF International (JJK); The University of Oulu & The Research Council of Finland Profi 326291 (VK); European Union’s Horizon 2020 research and innovation programme under grant agreement no. 848158 (EarlyCause) (VK); Wellcome Trust (225790/Z/22/Z) and the UK Research and Innovation Medical Research Council (MC_UU_00040/01) (VK). The study funders were not involved in the design of the study; the collection, analysis, and interpretation of data; writing the report; and did not impose any restrictions regarding the publication of the report.
: The authors declare that there are no relationships or activities that might bias, or be perceived to bias, their work.
: JJK, VK and DG designed the study. JJK, VK and JL curated data. TEH and EKK analysed and visualised the data under supervision of JL, JJK and VK. TEH, EKK and JJK wrote the first draft of the manuscript. All authors reviewed and edited the manuscript and approved the final version to be published. All authors had access to data, and JJK, VK, JL, TEH and EKK accessed and verified the data. JJK, VK, TEH and EKK are guarantors for this article.