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Authors
Swensen, Adam C.
Piehowski, Paul D.
Chen, Jing
Chan, X’avia Y.
Kelly, Shane S.
Petyuk, Vladislav A.
Moore, Ronald J.
Nasif, Lith
Butterworth, Elizabeth A.
Atkinson, Mark A. https://orcid.org/0000-0001-8489-4782
Kulkarni, Rohit N. https://orcid.org/0000-0001-5029-6119
Campbell-Thompson, Martha https://orcid.org/0000-0001-6878-1235
Mathews, Clayton E. https://orcid.org/0000-0002-8817-6355
Qian, Wei-Jun https://orcid.org/0000-0002-5393-2827
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Funding
Funding for this research was provided by:
National Institute of Diabetes and Digestive and Kidney Diseases (R01DK122160, R01DK123329, R01DK67536, U54DK127823, UC4 DK104167, UC4DK104155)
National Institute of Allergy and Infectious Diseases (P01AI04228)
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Article History
Received: 13 September 2024
Accepted: 12 February 2025
First Online: 2 June 2025
Acknowledgements
: We thank the donors and families of the donors for their invaluable contribution to our research and their help to further understand and hopefully cure type 1 diabetes. This research was performed with the support of the Network for Pancreatic Organ Donors with Diabetes (nPOD), a collaborative type 1 diabetes research project sponsored by Breakthrough T1D (formerly known as JDRF). Organ Procurement Organizations (OPO) partnering with nPOD to provide research resources are listed at . The authors thanks S. Rich and D. Michalek (University of Virginia) for their assistance in determining HLA risk alleles. The proteomics work was performed in the Environmental Molecular Sciences Laboratory, a national scientific user facility sponsored by the DOE and located at Pacific Northwest National Laboratory, which is operated by Battelle Memorial Institute for the DOE under Contract DE-AC05-76RL0 1830. This work used a LEICA 7000 laser microdissection microscope purchased with an NIH shared instrumentation grant S10OD016350 and operated by the University of Florida Molecular Pathology Core (RRID:SCR_016601).
: The LC-MS raw datasets that support the findings of this study have been deposited in the online repository: MassIVE () with accession no. MSV000090212.
: This work was supported by NIH Grants R01DK122160, R01DK123329, UC4 DK104167, UC4DK104155, UC4DK104194, U54DK127823, R01DK67536, P01AI042288, R01DK135081 and JDRF 5-SRA-2018-557-Q-R.
: The authors declare that there are no relationships or activities that might bias, or be perceived to bias, their work.
: All authors made substantial contributions to the conception or design of the work or the acquisition, analysis, or interpretation of data; and drafting or reviewing the article critically for important intellectual content. All authors approved the final version to be published. WJQ and CEM are responsible for the integrity of the work as a whole.
