Zapardiel-Gonzalo, Jose https://orcid.org/0000-0002-9098-1652
Ziegler, Anette-Gabriele https://orcid.org/0000-0002-6290-5548
Bonifacio, Ezio https://orcid.org/0000-0002-8704-4713
Funding for this research was provided by:
Leona M. and Harry B. Helmsley Charitable Trust (2018PG-T1D022, G-2103-05036)
Novo Nordisk Foundation Center for Basic Metabolic Research (NNF22SA0081044)
Bundesministerium für Bildung und Forschung (German Center for Diabetes Research (DZD e.V.))
Technische Universität Dresden
Article History
Received: 3 December 2024
Accepted: 4 March 2025
First Online: 12 April 2025
Acknowledgements
: We thank R. Oram, S. Sharp, D. Fraser and the Exeter team for their assistance in calculating the GRS2 in our cohorts.
: The de-identified individual data that underlie the results can be shared. Requests will be honoured from researchers who provide a methodologically sound proposal and who complete a Data Use Agreement with the Helmholtz Zentrum München. Requests should be directed by email to the corresponding author.
: This study was supported by a grant from the EASD-Novo Nordisk Foundation Diabetes Prize for Excellence NNF22SA0081044, the German Center for Diabetes Research (DZD e.V.), and The Leona M. and Harry B. Helmsley Charitable Trust (Helmsley) grants 2018PG-T1D022 and G-2103-05036.
: The authors declare that there are no relationships or activities that might bias, or be perceived to bias, their work.
: JZ-G, A-GZ and EB conceived and designed the study. A-GZ created the cohorts and acquired the data. JZ-G and EB collected and analysed the data. EB drafted and JZ-G and A-GZ reviewed and edited the manuscript. All authors have approved the final manuscript. EB is the guarantor of this work.