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Article History

Received: 17 November 2024

Accepted: 14 February 2025

First Online: 10 April 2025

Acknowledgements

: The authors would like to express their gratitude to all study participants for their participation. Furthermore, we thank Lisa Buus, Elsebeth Hornemann and Eva Schriver (Medical/Steno Aarhus Research Laboratory, Aarhus University, Denmark) for their skilled technical expertise during the study, and Helle Zibrandtsen (Medical/Steno Aarhus Research Laboratory, Aarhus University, Denmark) for thorough training and assistance with laboratory procedures. Some of the data from the present study were presented as an abstract at the EASD Annual Meeting in 2022.

: The corresponding author will make data available upon reasonable request.

: The study was financially supported by the Novo Nordisk Foundation (NNF19OC0058872) and the Health Research Foundation of Central Denmark Region. The study funders had no involvement in the study design, the collection, analysis and interpretation of data, or in the writing of the report, and did not impose any restrictions on publication of the report.

: The authors declare that there are no relationships or activities that might bias, or be perceived to bias, their work.

: MB, MVS, NR and NM conceived and designed the study. MB, MGBP and JV conducted the study. MB analysed the data. MB, MVS, NR, NJ and NM contributed to the interpretation of results. MB drafted the manuscript. All authors reviewed and approved the final manuscript. NM and MB are the guarantors of the work, accept full responsibility for the work, have access to the data, and controlled the decision to publish.