Document is current

Article History

Received: 5 May 2025

Accepted: 4 July 2025

First Online: 4 September 2025

Acknowledgements

: The authors acknowledge the skilled technical assistance of Olaya Garcia (Institut de Recerca Sant Pau, Barcelona, Spain).

: The datasets used and/or analysed during the current study are available from the corresponding author on reasonable request. The GSE245003 miRNA profile was downloaded from the Gene Expression Omnibus (GEO; ). The new data discussed in this publication have been deposited in GEO and are accessible through GEO accession number GSE283040.

: Open Access funding provided thanks to the CRUE-CSIC agreement with Springer Nature. This research was funded by grant MICIN-PID2019-107160RB-I00 to LB; by grants from Instituto de Salud Carlos III: Red Española de Terapias Avanzadas TERAV-RD21/0017/0013 to LB and GA; by a grant from the Centro de Investigación Biomédica en Red Cardiovascular (CIBERCV-CB16/11/00411) to LB; and by grant PI23/01136 to GA, co-funded by Fondo Europeo de Desarrollo Regional (FEDER) ‘Una Manera de Hacer Europa’. We thank the Generalitat of Catalunya (Secretaria d’Universitats i Recerca, Departament d’Economia i Coneixement, 2021 SGR 01006) and the Fundación Investigación Cardiovascular Fundación Jesus Serra for their continued support.

: The authors declare that there are no relationships or activities that might bias, or be perceived to bias, their work.

: GA, AC-U, MTB, EP and LB contributed to the conceptualisation and design of the present study. EP, FM, MTB and GV acquired and processed the samples, and AC-U analysed the data. GA and AC-U wrote the manuscript, MTB, GV and LB reviewed and edited the manuscript, and all authors reviewed and approved the final version of the manuscript. GA is the guarantor of the present study, and, as such, had full access to all data in the study and takes full responsibility for the integrity of the data and the accuracy of the data analyses.