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Article History
Received: 12 December 2025
Accepted: 5 May 2026
First Online: 26 August 2026
Ethics
Acknowledgements: All authors are grateful to the respective participants of the cohorts mentioned in this paper and acknowledge their contribution. Without their selfless contribution to science, there would be no review on what the cohorts have taught us.
Funding: No study funders were involved in the design of this review; the collection, analysis, and interpretation of data; writing the report; or the decision to submit the report for publication. Work in SHK’s laboratory is partially funded by NIH P30DK116074. MRR was supported in part by NIH/NIDDK grant K01 DK141963.
Authors’ relationships and activities: FR and AB are Associate Editors of Diabetologia . The other authors declare that there are no relationships or activities that might bias, or be perceived to bias, their work.
Contribution statement: All authors were responsible for drafting the article and revising it critically for important intellectual content. All authors approved this version to be published.