Text and Data Mining valid from 2019-02-11
Received: 25 September 2018
Accepted: 23 January 2019
First Online: 11 February 2019
Compliance with ethical standards
: Daniel De Backer: consultant to and material for studies by Edwards Lifesciences. Maurizio Cecconi: consultancy for Edwards Lifesciences, LiDCO, Cheetah, Masimo. Jeffrey Lipman: MSD (Australia)—Antibacterials Advisory Board; honoraria for lectures—Pfizer South Africa, MSD South Africa; committee—Pfizer International 2018 Anti-Infectives. Flavia Machado: member of steering committee for BASIC study, for which drug was supplied by Baxter. Sheila Nainan Myatra: no conflict of interest. Marlies Ostermann: research funding from Ja Jolla Pharma. Anders Perner: Dept. of Intensive Care at Rigshospitalet has received support for research from CSL Behring, Fresenius Kabi, and Ferring Pharmaceutical. Jean-Louis Teboul: member of the medical advisory board of Pulsion/Getinge (Germany). Jean Louis Vincent: no conflict of interest. Keith Walley: no conflict of interest.
: An approval by an ethics committee was not applicable.