Updates are available Correction dated 2022-03-18

Article History

Received: 12 October 2021

Accepted: 21 December 2021

First Online: 1 February 2022

Declarations

:

: SH report grants from the Federal Ministry of Education and Research (BMBF), lecture fees from Pfizer, MSD, InfectoPharm, Advanz and Philips, support for attending meetings from Pfizer and Advanz. AB reports lecture fees from MSD Sharp & Dohme GmbH, Pfizer Pharma GmbH, Fresenius Medical Care (FMC), Labor Volkmann (Karlsruhe). TB reports lecture fees from CSL Behring GmbH, Schöchl medical education GmbH, Biotest AG, Baxter Deutschland GmbH, Boehringer Ingelheim Pharma GmbH, Astellas Pharma GmbH, B. Braun Melsungen AG, MSD Sharp & Dohme GmbH, support for participation in a Data Safety and Monitoring Board for Baxter Deutschland GmbH and and research funding from Deutsche Forschungsgemeinschaft (DFG), Dietmar Hopp Stiftung, Stiftung Universitätsmedizin Essen. Heidelberger Stiftung Chirurgie, Innovationsfonds des Gemeinsamen Bundesausschusses (G-BA). SN reports grants from the Center for Sepsis Control and Care (CSCC) by the Ministry of Education and Research (BMBF), Grant-no. 01EO1502. SK reports grants from Ambu, Daiichi Sankyo, ETView Ltd, Fisher & Paykel, Pfizer and Xenios, consulting fees from Bayer, Fresenius, Gilead, MSD and Pfizer, lecture fees from Astra, C.R.Bard, Baxter, Biotest, Cytosorbents, Daiichi Sankyo, Fresenius, Gilead, Mitsubishi Tanabe Pharma, MSD, Pfizer, Philips and Zoll. MW reports lecture fees from MSD, Gilead, Shionogi, Pfizer, support for participation in a Data Safety and Monitoring Board for MSD, Gilead, Shionogi, Eumedica, Biotest. All other authors declare no competing interests.

: The trial was approved by the relevant ethics committees in all study sites.

: Written informed consent was obtained from all patients or from their surrogates.

: All authors approved the manuscript for submission.