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Authors
Shepherd, Joanna M. https://orcid.org/0000-0001-8180-8842
Ross, Jennifer
Anton, Lourdes
Rourke, Claire
Brentnall, Adam R.
Tarning, Joel
White, Nicholas J.
Thiemermann, Christoph
Brohi, Karim
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Funding
Funding for this research was provided by:
Wellcome Trust (101012/Z/13/Z)
Department of Health (HICFR7405)
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Article History
Received: 16 February 2023
Accepted: 27 May 2023
First Online: 20 July 2023
Declarations
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: The authors declare they have no conflict of interest, including financial interests, activities, relationships, and affiliations in relation with the TOP-ART Trial.
: The trial was authorized by the Medicines and Healthcare products Regulation Authority (ref: 21313/0052/001-0001) on the 22nd January 2016 and approved by London City and East Research Ethics Committee (reference: 16/LO/003) on 11th March 2016. The trial was registered prospectively with the EU Clinical Trials Register (Identifier 2015-000301-40) and the ISRCTN (Identifier 15731357) on the 28th August 2015.
: The trial was conducted in accordance with the Declaration of Helsinki. Written informed consent was obtained from all participants or, in cases of impaired capacity, their closest relative or appropriate representative.
