Nyholm, Benjamin http://orcid.org/0000-0002-3905-4909
Grand, Johannes
Obling, Laust E. R.
Hassager, Christian
Møller, Jacob Eifer
Schmidt, Henrik
Othman, Marwan H.
Kondziella, Daniel
Horn, Janneke
Kjaergaard, Jesper
Clinical trials referenced in this document:
Documents that mention this clinical trial
Impact of Blood Pressure Targets in Patients With Heart Failure Undergoing Postresuscitation Care: A Subgroup Analysis From a Randomized Controlled Trial
https://doi.org/10.1161/circheartfailure.123.011437
Validating quantitative pupillometry thresholds for neuroprognostication after out-of-hospital cardiac arrest. A predefined substudy of the Blood Pressure and Oxygenations Targets After Cardiac Arrest (BOX)-trial
https://doi.org/10.1007/s00134-024-07574-6
Acute kidney injury after out-of-hospital cardiac arrest
https://doi.org/10.1186/s13054-024-04936-w
Blood Pressure and Oxygen Targets on Kidney Injury After Cardiac Arrest
https://doi.org/10.1161/circulationaha.123.066012
Funding for this research was provided by:
Novo Nordisk Fonden (NNF20OC0064043, NNF20OC0064043)
National Hospital
Article History
Received: 23 March 2024
Accepted: 26 July 2024
First Online: 20 August 2024
Declarations
:
: The study is supported by a grant from the Novo Nordisk Foundation (NNF20OC0064043) supporting the salary of BN and JK. JEM received institutional research grants from Abiomed and Novo Nordic Foundation outside submitted work. JG is supported by a research grant from the Danish Cardiovascular Academy, funded by the Novo Nordisk Foundation (NNF20SA0067242) and The Danish Heart Foundation. CH received grants from the Lundbeck Foundation (R186-2015–2132), Novo Nordisk Foundation (NNF20OC0064043), and The Danish Heart Foundation (21-R151-A10091-22200). On behalf of all authors, the corresponding author states that there is no conflict of interest for the remaining authors.
: Per protocol, permissions were obtained from the Regional Ethics Committee (ID: H-16033436) before initiating the main BOX-trial.
: The trial was conducted in accordance with the Declaration of Helsinki. Danish law allows for the immediate inclusion of patients in non-drug trials, requiring consent to be obtained as soon as possible after enrollment. Written informed consent was secured from a legal guardian and collected by a departmental doctor at the earliest opportunity following admission to the hospital. Once conscious, consent was obtained from patients through the same medical staff.
: This study is sponsor–investigator-initiated with no funding or involvement from pharmaceutical companies. The sponsor–investigator maintains authority over all aspects of the trial, including design, management, interpretation of results, and publication.
: Jesper Kjærgaard, consultant, MD, Ph.D., DMSc Department of Cardiology, The Heart Centre, Copenhagen University Hospital Rigshospitalet, Copenhagen, Denmark. Jesper.kjaergaard.05@regionh.dk.