Document is current

Article History

Received: 27 February 2024

Accepted: 2 August 2024

First Online: 26 August 2024

Declarations

:

: The authors declare no conflicts of interest.

: This study involving human participants was in accordance with the ethical standards of the institutional and national research committee and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards. For data obtained in the derivation cohort: In accordance with Dutch legislation and compliance with the European General Data Protection Regulation, there is no need to obtain consent when anonymous data are used. For data obtained in the reproduction cohort: The study received approval from the Institution’s Internal Review Board (Comité Ètic d’Investigació Clínica, registry number HCB/2020/0370). Local researchers maintained contact with a study team member and participating hospitals obtained local ethics committee approval. For data obtained in the Radboudumc cohort: Data collection and blood sampling were performed as part of a cohort study, which was carried out in accordance with the applicable rules concerning the review of research ethics committees and informed consent in the Netherlands. All patients or legal representatives were informed about the details of this cohort study and could decline to participate. For data obtained in the Amsterdam UMC cohort: Data collection was approved by the Amsterdam UMC ethics committee (AUMC 2020_065). Written informed consent was obtained from all patients or their legal representatives with an additional option of deferred consent using an opt-out method for incapacitated patients. For data obtained in the Jena cohort: Data collection was carried out as part of a cohort study on hepatic dysfunction in COVID-19, which was approved by the ethics committee of Jena University Hospital (2020-1797). As only data from routine care were used in this study, there was no need for informed consent according to state law.