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Authors
Göbel Andertun, Sara https://orcid.org/0009-0003-4709-9570
Wissendorff-Ekdahl, Anne https://orcid.org/0000-0001-8677-176X
Ullén, Susann
Cronberg, Tobias https://orcid.org/0000-0002-3442-3058
Friberg, Hans https://orcid.org/0000-0002-5588-0098
Jakobsen, Janus Christian https://orcid.org/0000-0002-3642-2120
Blennow Nordström, Erik https://orcid.org/0000-0003-1117-4412
Heimburg, Katarina https://orcid.org/0000-0002-2586-1638
Cariou, Alain https://orcid.org/0000-0003-3258-4672
Grejs, Anders Morten https://orcid.org/0000-0002-8850-2982
Haenggi, Matthias https://orcid.org/0000-0001-5845-031X
Hovdenes, Jan https://orcid.org/0000-0002-7415-0525
Robba, Chiara https://orcid.org/0000-0003-1628-3845
Rylander, Christian https://orcid.org/0000-0002-4534-7150
Taccone, Fabio Silvio https://orcid.org/0000-0003-0830-1628
Wise, Matt P. https://orcid.org/0000-0002-2763-4316
Young, Paul J. https://orcid.org/0000-0002-3428-3083
Nielsen, Niklas https://orcid.org/0000-0002-6013-126X
Lilja, Gisela https://orcid.org/0000-0003-1860-1456
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Clinical Trials BETA
Clinical trials referenced in this document:
nct02908308 at ClinicalTrials.govDocuments that mention this clinical trial
Ventilation management and outcomes in out-of-hospital cardiac arrest: a protocol for a preplanned secondary analysis of the TTM2 trial
https://doi.org/10.1136/bmjopen-2021-058001
Oxygen targets and 6-month outcome after out of hospital cardiac arrest: a pre-planned sub-analysis of the targeted hypothermia versus targeted normothermia after Out-of-Hospital Cardiac Arrest (TTM2) trial
https://doi.org/10.1186/s13054-022-04186-8
Impact of frailty on mortality, functional outcome, and health status after out-of-hospital cardiac arrest: insights from the TTM2-trial
https://doi.org/10.1007/s00134-025-08185-5
Standardised and automated assessment of head computed tomography reliably predicts poor functional outcome after cardiac arrest: a prospective multicentre study
https://doi.org/10.1007/s00134-024-07497-2
Ventilatory settings in the initial 72 h and their association with outcome in out-of-hospital cardiac arrest patients: a preplanned secondary analysis of the targeted hypothermia versus targeted normothermia after out-of-hospital cardiac arrest (TTM2) trial
https://doi.org/10.1007/s00134-022-06756-4
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Funding
Funding for this research was provided by:
Vetenskapsrådet
the Gorthons Foundation
the Knutsson Foundation
Hans-Gabriel och Alice Trolle-Wachtmeisters stiftelse för medicinsk forskning
Hjärt-Lungfonden
Lund University
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Article History
Received: 7 July 2025
Accepted: 21 October 2025
First Online: 10 November 2025
Declarations
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: SGA, AWE, SU, TC, HF, JCJ, EBN, KH, AC, MH, JH, CRy, FST, PJY, NN, GL report no conflicts of interest. CRo received fees as a speaker from BD. MPW has served on advisory boards for DRW Diagnostics and the Clinical Expert NICE Advice Service. CR is Deputy Editor for Intensive Care Medicine. She has not taken part in the review or selection process of this article.
: The study was approved by the Regional Ethics Committee at Lund University (2015/228) and in all participating countries. The study was performed in accordance with the ethical standards as laid down in the 1964 Declaration of Helsinki and its later amendments.
