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Epistane, an anabolic steroid used for recreational purposes, causes cholestasis with elevated levels of cholic acid conjugates, by upregulating bile acid synthesis (CYP8B1) and cross-talking with nuclear receptors in human hepatocytes

Crossref DOI link: https://doi.org/10.1007/s00204-019-02643-y

Published Online: 2020-01-01

Published Print: 2020-02

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Petrov, Petar D. https://orcid.org/0000-0001-9697-4317
Fernández-Murga, Leonor https://orcid.org/0000-0001-7123-9834
Conde, Isabel

Martínez-Sena, Teresa

Guzmán, Carla

Castell, José Vicente https://orcid.org/0000-0003-1179-6430
Jover, Ramiro https://orcid.org/0000-0002-4914-5804
Funding

Funding for this research was provided by:

FP7 Health (602156)

Instituto de Salud Carlos III (PI17/01089)

Instituto de Salud Carlos III (CD18/00158)
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Text and Data Mining valid from 2020-01-01

Version of Record valid from 2020-01-01
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Article History

Received: 27 September 2019

Accepted: 2 December 2019

First Online: 1 January 2020

Compliance with ethical standards

:

: The authors declare that they have no conflict of interests.

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