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2,2',4,4'-tetrabromodiphenyl ether (BDE-47) induces early hearing loss in guinea pigs via activating AhR to trigger mitochondrial and endoplasmic reticulum stress-regulated autophagy

Crossref DOI link: https://doi.org/10.1007/s00204-025-04154-5

Published Online: 2025-08-20

Published Print: 2025-11

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Tang, Jie

Zhang, Li

Yang, Yujia

Wang, Chunji

Zhang, Fang

Yu, Muxin

Zhang, Nenghua

Xu, Guangtao

Hu, Bo

Shi, Meiling

Xu, Long https://orcid.org/0000-0001-9727-8575
Funding

Funding for this research was provided by:

National Natural Science Foundation of China (22206059)

Basic Public Welfare Planning Project of Zhejiang Province, China (LQ24B070003)

Medical Health Science and Technology Project of Zhejiang Provincial Health Commission (2023RC101)

Sci-Tech Planning Project of Jiaxing, China (2024AY30005)

Sci-Tech Planning Project of Jiaxing, China (2024AY30010)

Student Research Training Program (8517241008)
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Text and Data Mining valid from 2025-08-20

Version of Record valid from 2025-08-20
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Article History

Received: 17 June 2025

Accepted: 11 August 2025

First Online: 20 August 2025

Declarations

:

: This manuscript has not been published in part or in entirety by another journal. The study design was approved by the Ethics Review Committee for Animal Research at College of Medicine, Jiaxing University. All the authors have approved that this manuscript is published to your esteemed journal. The authors declare no competing financial interest.

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