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Species, cell proliferation state and oxygen partial pressure are major factors in the in vitro toxicity of repurposed potential ADPKD drugs in human and murine renal proximal tubule cells

Crossref DOI link: https://doi.org/10.1007/s00204-026-04472-2

Published Online: 2026-06-27

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Sotiropoulou, Paraskevi

Gerdemann, Andrea

Jovanovic, Stefan

Humpf, Hans-Ulrich

Bürkle, Alexander

Dietrich, Daniel R.
Funding

Funding for this research was provided by:

Universität Konstanz
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Text and Data Mining valid from 2026-06-27

Version of Record valid from 2026-06-27
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Article History

Received: 12 May 2026

Accepted: 28 May 2026

First Online: 27 June 2026

Declarations

:

: The authors declare that they have no conflict of interest.

: The manuscript does not contain clinical studies or patient data.

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