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Authors
Li, Bingxin
Jiang, Xiaojie
Liu, Chang
Ma, Yun
Zhao, Ruining
Zhang, Haijun
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Funding
Funding for this research was provided by:
University Natural Science Research Project of Anhui Province (2023AH050342, 2023AH040055)
Natural Science Foundation of Anhui Province (2308085MC79)
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Article History
Received: 15 May 2024
Accepted: 24 June 2024
First Online: 3 July 2024
Declarations
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: This study was performed in line with the principles of the Declaration of Helsinki. Approval was granted by the Ethics Committee of The Liaoning Changsheng Biotechnology (CSE20201017).
: Not applicable.
: Not applicable.
: The authors declare no competing interests.
: Male C57BL/6 mice, 5–7 weeks old, were sourced from Liaoning Changsheng Biotechnology (Approval No. SCXK(Liao)2020–00001). We divided the mice into five groups with seven animals each: control, BLM (5 mg/kg), two BLM + JGT-E groups treated with 50 mg/kg and 100 mg/kg, and BLM + PFD (100 mg/kg) group. After acclimating for 1 week, the JGT-E treatment was administered orally to the respective groups for 3 days. Mice designated for BLM treatment received a 5 mg/kg dose intratracheally, while controls were given saline. Both JGT-E and PFD treatments were continued daily, based on individual body weights. Three weeks later, the mice were euthanized for analysis.
