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Dabigatran attenuates methotrexate-induced hepatotoxicity by regulating coagulation, endothelial dysfunction, and the NF-kB/IL-1β/MCP-1 and TLR4/NLRP3 signaling pathways

Crossref DOI link: https://doi.org/10.1007/s00210-024-03567-w

Published Online: 2024-11-11

Published Print: 2025-05

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

El-Dessouki, Ahmed M.

Alzokaky, Amany A.

Raslan, Nahed A.

Ibrahim, Samar

Selim, Heba Mohammed Refat M.

Al-Karmalawy, Ahmed A.
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Text and Data Mining valid from 2024-11-11

Version of Record valid from 2024-11-11
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Article History

Received: 8 August 2024

Accepted: 23 October 2024

First Online: 11 November 2024

Declarations

:

: The protocol for the animal study received approval from the Research Ethics Committee at the Faculty of Pharmacy, Ahram Canadian University, Egypt (Ethics code: REC0524).

: This is not applicable

: The authors declare no competing interests.

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