Li, Bingxin
Zhao, Ruining
Jiang, Xiaojie
Liu, Chang
Ma, Yun
Zhang, Haijun
Funding for this research was provided by:
University Natural Science Research Project of Anhui Province (2023AH050342)
University Natural Science Research Project of Anhui Province (2023AH040055)
Natural Science Foundation of Anhui Province (2308085MC79)
Article History
Received: 8 October 2024
Accepted: 19 December 2024
First Online: 27 December 2024
Declarations
:
: This study was performed in line with the principles of the Declaration of Helsinki. Approval was granted by the Ethics Committee of The Liaoning Changsheng Biotechnology (CSE20201017).
: Not applicable
: Not applicable.
: The authors declare no competing interests.
: Male C57BL/6 mice (5–7 weeks old) were obtained from Liaoning Changsheng Biotechnology (Approval No. SCXK(Liao)2020-00001). The mice were randomly assigned into five groups. Following 1 week of acclimatization, mice in the drug treatment groups were administered the extract or PFD orally for three consecutive days. Subsequently, mice in the BLM groups were intratracheally instilled with 5 mg/kg BLM, while the control group received an equivalent volume of saline. Three weeks post-treatment, the mice were euthanized for sample collection and analysis.