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Repurposing rupatadine to attenuate ovarian ischemia reperfusion in rats through modulation of PAF/NF-κB/TNF-α/IL-1β; HIF-1α/VEGF/Caspase 3 signaling pathways

Crossref DOI link: https://doi.org/10.1007/s00210-025-04567-0

Published Online: 2025-09-05

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Khalaf, Hanaa Mohamed

Ahmed, Sara M.

Abdelmonaem, Alyaa Abdelfattah

Saleh, Rabeh Khairy

Mohamed, Abdelaleem Abdelnour

Ali, AbdelHamid Sayed AboBakr

Adel, Mohamed

Mohamed, Heba Reda

Kamel, Heba S.

Abdelzaher, Walaa Yehia https://orcid.org/0000-0001-6511-1797
Funding

Funding for this research was provided by:

Minia University
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Text and Data Mining valid from 2025-09-05

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Article History

Received: 28 May 2025

Accepted: 18 August 2025

First Online: 5 September 2025

Declarations

:

: The animal study was reviewed and approved by the Institutional Ethical Committee, Medicine Faculty, Minia University, Egypt according to the NIH Guide for taking care and use of laboratory animals (Approval No: 1296:10/2024).

: The authors declare no competing interests.

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