Text and Data Mining valid from 2019-03-04
Received: 31 December 2018
Revised: 11 February 2019
Accepted: 18 February 2019
First Online: 4 March 2019
Compliance with ethical standards
: The authors state that they have obtained appropriate Institutional Review Board approval or have followed the principles outlined in the Declaration of Helsinki for all animal experimental investigations.
: All of the authors are employees of Genentech. The authors have no other relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript apart from those disclosed.