Siciliano, Angela Marika
Moro, Federico
De Simone, Giulia
Pischiutta, Francesca
Morabito, Aurelia
Pastorelli, Roberta
Brunelli, Laura
Zanier, Elisa R.
Davoli, Enrico http://orcid.org/0000-0003-0933-1351
Funding for this research was provided by:
Paguni Lugli Family (In memory of Rodolfo Paguni)
Article History
Received: 2 April 2024
Revised: 26 June 2024
Accepted: 27 June 2024
First Online: 1 August 2024
Declarations
:
: Procedures involving animals and their care were conducted in conformity with the institutional guidelines at the Istituto di Ricerche Farmacologiche Mario Negri IRCCS in compliance with national standards (D.lgs 26/2014; Authorization n. 19/2008-A issued March 6, 2008, by Ministry of Health); Mario Negri Institutional Regulations and Policies providing internal authorization for persons conducting animal experiments (Quality Management System Certificate – UNI EN ISO 9001:2015 – Reg. N° 6121); the NIH Guide for the Care and Use of Laboratory Animals (2011 edition), and EU directives and guidelines (EEC Council Directive 2010/63/UE). All animal experiments were designed in accordance with Animal Research: Reporting of In Vivo Experiments (ARRIVE) guidelines, with a commitment to refinement, reduction, and replacement, and using biostatistics to optimize the number of mice.
: The authors declare no competing interests.