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Inductively coupled plasma mass spectrometry as a sensitive non-radioactive alternative for quantitative analysis in drug metabolism studies based on fluorine detection

Crossref DOI link: https://doi.org/10.1007/s00216-026-06406-4

Published Online: 2026-02-23

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Wouters, Sam https://orcid.org/0000-0003-0919-8466
Cuyckens, Filip
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Text and Data Mining valid from 2026-02-23

Version of Record valid from 2026-02-23
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Article History

Received: 1 December 2025

Revised: 19 January 2026

Accepted: 9 February 2026

First Online: 23 February 2026

Declarations

:

: The Belgian J&J facilities are AAALAC accredited and all animal experimentation performed was reviewed and approved by the institutional Ethical Committee on Animal Experiments (EDC) in accordance with legislation within the framework of EU-directive 2010/63/EU and the Belgian royal decree of 29/05/2013/. The animal welfare body (AWB) provides guidance in animal welfare connected to the purchase, housing, care, and use of laboratory animals and application of the 3Rs. AWB is responsible for assisting in the supervision of the correct application of the project procedures as approved by the ECD.

: The authors declare no competing financial or nonfinancial interests.

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