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Visualization of relative 11β-hydroxylase (CYP11B1) activity in human cortisol-producing adrenocortical adenoma (CPA) using mass spectrometry imaging-based enzyme histochemistry

Crossref DOI link: https://doi.org/10.1007/s00216-026-06518-x

Published Online: 2026-05-13

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Nagano, Erika

Fujita, Masamichi

Umakoshi, Hironobu

Ogasawara, Tatsuki

Ogawa, Yoshihiro

Ogawa, Seishi

Eto, Masatoshi

Odake, Kazuki

Shimma, Shuichi
Funding

Funding for this research was provided by:

Japan Society for the Promotion of Science (JP22H04993)

Japan Society for the Promotion of Science (JP25K11808)

The University of Osaka
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Article History

Received: 19 December 2025

Revised: 31 March 2026

Accepted: 13 April 2026

First Online: 13 May 2026

Declarations

:

: The study protocol was reviewed and approved by the Ethics Committees of both Kyushu University and the University of Osaka (Reference number: 21025-03).

: The authors declare no conflicts of interest.

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