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Article History

Received: 1 April 2018

Accepted: 25 May 2018

First Online: 16 June 2018

Compliance with Ethical Standards

:

: NN has received consultant and speaker fees from Eli Lilly, Amgen and MSD. BL has received research grants from Eli Lilly, Novo Nordisk, Amgen and Orkla Health, and advisory board and honoraria for speaking at symposia from Eli Lilly, Merck, Amgen and UCB. OL has received lecture fees from Eli Lilly and Amgen. E.Lespessailles has received honoraria for speaking at symposia, financial support for attending symposia and financial support for educational programs from Amgen (France) and Eli Lilly (France) and speaker fees from Expanscience, Novartis and Servier. GK has received honoraria for speaking at symposia. TK has received speaker honoraria from Eli Lilly, Amgen and Novartis. TN has received speaker honoraria from Eli Lilly, Amgen and Pliva, and financial support for attending symposia from Amgen and ESCEO-Eli Lilly 2015 Scholarship. PE is an advisory board member with Amgen, MSD and Eli Lilly and Company; was at the speaker’s bureau with Amgen and Eli Lilly and owns stocks from Novo Nordisk A/S. FM, HP and E.Lindh are employees of Eli Lilly and Company. TM is an employee and stock owner of Eli Lilly and Company.

: The ExFOS study was approved by local ethics committees or review boards, depending on local requirements, and was conducted in compliance with all applicable laws, regulations and guidelines.

: All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards. Written informed consent was obtained from all individual patients included in the study.