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Regular Proton-Pump Inhibitor Intake is Associated with Deterioration of Peripheral Bone Mineral Density, Microarchitecture, and Strength in Older Patients as Assessed by High-Resolution Peripheral Quantitative Computed Tomography (HR-pQCT)

Crossref DOI link: https://doi.org/10.1007/s00223-025-01420-7

Published Online: 2025-10-22

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Heilmeier, Ursula

Siegenthaler, Alexandra

Meyer, Ursina

Boensch, Marie

Kistler-Fischbacher, Melanie

de Godoi Rezende Costa Molino, Caroline

van Rietbergen, Bert

Lang, Wei

Rizzoli, René

Theiler, Robert

Egli, Andreas

Bischoff-Ferrari, Heike Annette
Funding

Funding for this research was provided by:

Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung (PP00B-114864)

Velux Stiftung (441)

Baugarten Stiftung

ECTS Academy Personal Reserach Grant

University of Zurich
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Text and Data Mining valid from 2025-10-22

Version of Record valid from 2025-10-22
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Article History

Received: 8 October 2024

Accepted: 4 August 2025

First Online: 22 October 2025

Declarations

:

: All authors besides BvR declare that they do not have any conflicts of interests BvR is a consultant for Scanco Medical AG and has received grant support from Amolyt Pharma and Avania.

: Ethical Approval No. STZ 20/07, granted by ethical committee of the Canton of Zurich. Ethical Approval No. BASEC 2019-01790 granted by the Swiss Association of Research Ethics Committees.

: No animals were harmed in this study. The study was approved by the Ethics Committee of the Canton Zürich and the Swiss Agency for Therapeutic Products, and written informed content was given by all study participants prior to enrolment.

: Available.

: Available and included in general consent that all participants signed prior to participation.

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